baseclick代理产品之BCFA-246-5mg，Tri-β-GalNAc-PEG3-Azide

Tri-β-GalNAc-PEG3-Azide


Tri-β-GalNAc-PEG3-Azide 可通过铜催化叠氮化物-炔烃化学 (CuAAC) 用 Tri-GalNAc 部分点击标记炔烃或 DBCO 修饰靶标。Tri-GalNAc 结构可被去唾液酸糖蛋白受体 (ASGPR) 识别，因此可用于将生物分子作为 siRNA 靶向递送至肝脏组织。

Tri-β-GalNAc-PEG3-Azide enables the possibility to click label an Alkyne or DBCO modified target with an Tri-GalNAc moiety by copper-catalyzed Azide-Alkyne Chemistry (CuAAC). The Tri-GalNAc structure is recognized by the desialic acid glycoprotein receptor (ASGPR) and can be therefore used to target delivery of biomolecules as siRNA to liver tissue.

• Molecular Formula

  C₇₀H₁₂₅N₁₃O₃₁

• Shelf Life

  12 months unopened after receipt

• Storage Conditions

  -20 °C, dark

• Molecular Weight

  1644.8 g/mol

• Purity

  ≥ 95% (HPLC)

• Physical State

  white solid

• CAS Number

  n.a.

• Additional name

  Tri-β-GalNAc-PEG3-N3, (β-D-GalNAc)3-PEG3-N3, (β-D-GalNAc-sp)3-NHC(O)-PEG3-N3

• Solubility

  H2O, DMSO

• Preparation/Handling

  For a 10 mM solution add 304 μL to 5 mg.
  For a 10 mM solution add 608 μL to 10 mg.